Columbus Crew will contest the 2026 US Open Cup final against St. Louis CITY SC on Wednesday, October 21 at 8 pm ET/5 pm PT at ScottsMiracle-Gro Field in Columbus, Ohio. The match airs on Paramount+ and CBS Sports Network. Columbus seek their second US Open Cup title after winning in 2002, while St. Louis target their first-ever trophy.

Columbus reached the final by defeating Orlando City 2-1 in the semifinals, with goals from Josef Martínez and Brais Méndez. The Crew's path included victories over Richmond Kickers (3-0), One Knoxville SC (4-1), and New York City FC (1-0). Columbus operate under interim coach Laurent Courtois following a May coaching change.

St. Louis claimed a 3-0 semifinal victory over Colorado Rapids with goals from Sang Bin Jeong, Simon Becher and Alexandru Mățan. The CITY SC squad advanced through wins over FC Tulsa (4-0), Chicago Fire FC (2-1), and a penalty shootout against Houston Dynamo FC after a 2-2 draw. The champion earns a 2027 Concacaf Champions Cup berth plus prize money.