Spain will compete for first place against England in their Nations League decider without three injured Barcelona players: Rodri, Dani Olmo and Eric García. Coach Luis de la Fuente has called up three uncapped players to cover the absences: Betis goalkeepers Álvaro Valles and Antonio Roca, and Real Madrid academy defender Jacobo Ramón. Víctor Muñoz was also ruled out due to injury.

Spain enter the match in strong form, having won 11 consecutive matches. They defeated Croatia 2-1 on 6 October with Mikel Merino scoring twice. England also won on that date, beating Czechia 3-0 with Harry Kane netting a brace.

Several Spanish players will face a tight schedule. Barcelona and Atlético Madrid play each other on Sunday 8 November at 21:00 at the Riyadh Air Metropolitano, with the squad reporting on Monday 9 November. Spain then travel to Prague to face Czechia on Thursday 12 November at 20:45 in the Epet Arena.